Ultimate Glutathione contains four natural agents shown to boost glutathione levels
Why is this important?
- Glutathione is considered to be the most important cellular water-soluble antioxidant.
- Glutathione levels decline with age, allowing more free radical damage to accumulate, which harms our cells, ages our body and causes genetic mutations.
- Glutathione depletion and polymorphism are also shown to contribute to the development of Parkinson’s disease and other neurodegenerative conditions.
- Glutathione is also a key detoxification (conjugating) agent in phase II detoxification reactions that occur in the liver, skin, intestinal and kidney cells. The age-related depletion in glutathione impairs the body’s ability to remove dangerous substances from the body. Various medications also deplete glutathione (most notably acetaminophen), which increase risk of liver damage and liver failure. (Acetaminophen use is the leading cause of drug-induced liver failure in this part of the world – because it depletes glutathione)
- Because glutathione is not absorbed from the gut, studies show that the way to raise glutathione in the body is by supplementing with natural agents shown to increase glutathione synthesis. These four natural agents include: N-acetylcysteine, Alpha-lipoic acid, L-Glutamine and Milk Thistle (standardized to 80 % Silymarin Flavonoid Content)
All Four of these Natural Glutathione-Raising Agents Are Found in Adeeva Ultimate GLX. In addition to supporting glutathione synthesis, these natural agents have other independent health effects of great importance, some of which include:
- Alpha-Lipoic Acid – this compound also declines with age and is required for energy production (co-factor for pyruvate dehydrogenase), in virtually all body cells. The decline in energy many people feel as they age is due to the decline in alpha-lipoic acid. Alpha-Lipoic acid (like melatonin) is a water-soluble and fat-soluble antioxidant. As such, it also works with CoQ10 to help prevent damage to the mitochondrial membrane, which reduces mitochondrial damage, dysfunction and supports mitochondrial renewal (biogenesis) – a key factor in longevity and healthy life expectancy.
- N-Acetylcysteine (NAC) – this compound also acts as an antioxidant and NAC supplementation has been shown to be helpful most notably in polycystic ovarian disease and Parkinson’s disease. NAC has also been shown to help remove heavy metals from the body, due to its high sulfur content.
- L-Glutamine – supplementation with this compound has been shown to reduce upper respiratory tract infections in endurance athletes, as L-glutamine is critical for energy production in immune cells (endurance exercise depletes L-glutamine levels). Supplementation with L-glutamine has also been shown to heal the intestinal lining in many gut-related conditions, as it is a primary fuel for intestinal lining cells (intestinal epithelial cells).
- Silymarin – this compound has also been shown to strengthen the body’s immune system and supplementation with Silymarin (from Milk thistle) has saved the lives of individuals who inadvertently ate poisonous, liver-damaging mushrooms (due to its ability to raise liver glutathione levels and help repair damage to liver cells).
The Bottom Line:
Anyone who is over the age of 45 should consider taking Adeeva Ultimate GLX to prevent the age-related decline in glutathione and alpha-lipoic acid in their cells. Individuals with various liver conditions, those taking more two or more medications daily, and/or taking acetaminophen regularly, those wanting to remove some heavy metals from their body each day and individuals with other health conditions mentioned above should speak to a qualified health care professional about the use of Ultimate GLX in their case.
Here is a link to Dr. Meschino’s most recent webinar on this subject, which includes all relevant scientific references:
https://adeevainfo.com/webinar-glutathione-and-its-precursors-in-health-and-anti-aging/
Recommended Supplements
Dr. James Meschino
ABOUT THE AUTHOR
Dr. James Meschino, DC, MS, ROHP, is an educator, author, and researcher having lectured to thousands of healthcare professionals across North America. He holds a Master’s Degree in Science with specialties in human nutrition and biology and is recognized as an expert in the field of nutrition, anti-aging, fitness, and wellness as well as the author of numerous books.
LMU-216 Diet and Aerobic Exercise Successful Against Resistant High Blood Pressure
Diet and Aerobic Exercise Successful Against Resistant High Blood Pressure
Source: Journal Circulation (September 2021)
Lifestyle Medicine Update (September 29, 2021)
A study published in the journal Circulation in September 2021 showed that a healthy eating program, weight loss, and improved aerobic fitness can significantly reduce blood pressure and improve heart health in people with resistant hypertension. Resistant Hypertension is defined as uncontrolled high blood pressure (130/80 mm Hg or higher), despite the use of three or more high blood pressure medications of different classes. Although estimates vary, resistant hypertension likely affects about 5% of the general global population and may affect 20% to 30% of adults with high blood pressure. Resistant hypertension is a dangerous problem to contend with, as it is associated with end-organ damage (such as kidney failure) and a 50% greater risk of adverse cardiovascular events, including stroke, heart attack, and sudden death. Anything that can reduce blood pressure in these individuals should be taken seriously.
In June 2021, the American Heart Association advised that physical activity is the optimal first treatment choice for adults with mild to moderately elevated blood pressure and blood cholesterol who otherwise have low heart disease risk. The September 2021 study in the journal, Circulation, known as the “Treating Resistant Hypertension Using Lifestyle Modification to Promote Health (TRIUMPH),” was the first to evaluate the impact of lifestyle modifications in people with resistant hypertension. The four month-study involved 140 adults with resistant hypertension, whereby about half the participants were assigned The DASH eating plan, rich in fruits, vegetables, low-fat dairy products, with limited salt intake, which aligns with the American Heart Association’s nutrition recommendations. They also performed exercise training in a supervised cardiac rehabilitation setting three times per week. The second group received a single informational session from a health educator and written guidelines on exercise, weight loss, and nutritional goals to follow on their own. The average age of participants was 63 years old. Forty-eight percent were women; 59% were Black adults’ 31% had type 2 diabetes, and 21% had existing chronic kidney disease. The results showed that the participants in the supervised exercise program had about a 12-point drop in systolic blood pressure, compared to 7 points in the self-guided group. Participants in the supervised program also had greater improvements in other key indicators of heart health, suggesting that they had a lower risk of a heart event in the future.
One of the researchers, Dr. Blumenthal, commented, “Our findings showed lifestyle modifications among people with resistant hypertension can help them successfully lose weight and increase their physical activity, and as a result, lower blood pressure and potentially reduce their risk of heart attack or stroke.” He also noted that, “the success of the supervised program doesn’t mean people with resistant hypertension can stop taking their medications; however, it suggests that they may want to talk with their physicians about possibly reducing the dosages or altering their medications based upon their lowered blood pressure values.” Then he concluded, “the most important point is that it is not too late to lower blood pressure by making healthy lifestyle choices. Adopting a healthy lifestyle pays huge dividends, even for people whose blood pressure remains elevated despite being on three or more antihypertensive medications”, he commented. In my personal experience, many physicians fail to emphasize the meaningful therapeutic effects of targeted dietary and exercise protocols for patients with high blood pressure and resistant hypertension. Diet and exercise exert important medicinal effects on the body in both preventing high blood pressure and helping to treat high blood pressure, including helping those with dangerous resistant hypertension, once again illustrating that lifestyle medicine should be a key component of self-health care throughout your entire lifetime.
I have included the reference for this information in the text below.
References:
1. James A. Blumenthal, Alan L. Hinderliter, Patrick J. Smith, Stephanie Mabe, Lana L. Watkins, Linda Craighead, Krista Ingle, Crystal Tyson, Pao-Hwa Lin, William E. Kraus, Lawrence Liao, Andrew Sherwood. Effects of Lifestyle Modification on Patients With Resistant Hypertension: Results of the TRIUMPH Randomized Clinical Trial. Circulation, 2021; https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.121.055329
2. https://www.sciencedaily.com/releases/2021/09/210927092147.htm
Eat Smart, Live Well, Look Great,
Dr. Meschino
Dr. James Meschino
ABOUT THE AUTHOR
Dr. James Meschino, DC, MS, ROHP, is an educator, author, and researcher having lectured to thousands of healthcare professionals across North America. He holds a Master’s Degree in Science with specialties in human nutrition and biology and is recognized as an expert in the field of nutrition, anti-aging, fitness, and wellness as well as the author of numerous books.
LMU-202 Low Iodine Intake from Plant-based Diets Increasing Risk of Neurological Defects in Children
Low Iodine Intake from Plant-based Diets Increasing Risk of Neurological Defects in Children
Source: Multiple Peer-reviewed Studies (see references below)
Lifestyle Medicine Update (May 5, 2021)
So, let’s talk about iodine. It’s not considered to be a really sexy topic and it hardly gets mentioned in the nutrition and wellness news of the day. But the fact is that recent dietary trends have resulted in a growing number of people who are becoming more and more iodine deficient. More specifically, many young people are now adopting the dietary practices of avoiding consumption of all dairy and animal products, including fish and using sea salt and other salt substitutes in place of common table salt, in an effort to consume all things natural. One of the unintended consequences is that an increasing number of young women now find themselves at increased risk of having children born with impaired neurological conditions, due to poor iodine intake. A small study in South Australia recently showed this finding, but a 2017 U.S. study found that nearly 2 billion people worldwide were iodine deficient, resulting in 50 million experiencing clinical side effects.
Of importance to young women is the fact that just mild to moderate iodine deficiency has been shown to affect language development, memory, and mental processing speeds in their offspring. In fact, the need for increased iodine intake occurs during pregnancy, but studies show that most women do not ingest the amount of iodine that is desirable leading up to becoming pregnant, nor do they consume the increased amount required during pregnancy and lactation, which is 220 and 290 mcg per day, respectively. As was stated at the 1990 World Summit for Children, “Iodine deficiency remains the single greatest cause of preventable brain damage and mental retardation worldwide. “Eliminating iodine deficiency was recognized as one of the most achievable of the goals that the 1990 World Summit for Children set for the year 2000. Unfortunately, the year 2000 has long come and gone and many women who live in modern countries, who have ample access to foods rich or fortified with iodine, are now avoiding these foods.
Dietary strategies such as using plant-based beverages (oat milk, soy milk, etc.) in place of dairy products, avoiding all dairy products, avoiding all meaty foods, including fish, and using Himalayan sea salt and other salt alternatives that are not fortified with iodine, as well as avoiding bread products, have lead to an increased number of young women becoming mild to moderately iodine-deficient, which does not present with any physical symptoms, but does lay the foundation for brain development problems in their children should these women become pregnant. I’m the first person to tell you that a more plant-based diet is desirable for many reasons, including reducing the risk of cardiovascular disease and many types of cancer. It’s also better for the environment, and the ecosystem, not to mention the animals themselves. But, it has to be done intelligently, not guided only by philosophical principles. An iodine food fortification program exists in many developed countries for a reason, which is to help avoid the consequences of widespread iodine deficiency and insufficiency, which commonly occurs in populations where iodine-rich and iodine fortified foods are not available.
The daily requirement for iodine for most adults is 150 mcg per day. As little as ¼ teaspoon of iodized salt contains 76 mcg of iodine. As well, many flours and bread doughs are enriched with iodine often providing 180-185 mcg in one slice of bread. Boling pasta with a bit of iodized salt provides 36 mcg of iodine in a 1 cup serving of pasta. Many non-fat yogurts contain up to 116 mcg of iodine in 8 oz. 1 cup of non-fat milk contains 85 mcg of iodine. Some seaweeds contain up to 230 mcg of iodine, whereas other ones contain very little – so you can’t depend only on seaweed as your source of iodine. Most fruits and vegetables and legumes contain very little or no iodine at all and 1 cup of soy milk has 7 mcg (not very much). Of course, fruits, vegetables, and legumes, including soy products are healthy food choices, but they don’t provide iodine in an appreciable amount. You’ll have to find that elsewhere. Some fish, like cod, have as much as 158 mcg of iodine in 3 oz, whereas 3 oz of shrimp only has about 13 mcg, so it varies from fish to fish and from seafood to seafood. For example, 3 oz of tuna has 17 mcg of iodine.
In our society, individuals who tend to ingest less than the desired amount of iodine include:
- People who avoid iodized salt
- Pregnant and breast-feeding women (because they have increased need)
- Vegans and people who eat few or no dairy products, seafood, or eggs.
In addition to increasing the risk of neurological deficits in offspring, mild to moderate iodine deficiency has also been linked to increased risk for thyroid cancer as well as breast and stomach cancer, in a number of studies. Iodine deficiency can also cause fibrocystic breast disease, which can be reversed in many cases via medically supervised iodine supplementation. As a rule, iodine supplementation is not something that is required for most people, as the dosage of safe levels of iodine supplementation is still being debated. We do know that iodine supplementation can be harmful if too high a dosage is ingested. For most of us, paying attention to food sources of iodine is a prudent strategy to employ. We are fortunate enough to live in a part of the world where iodine fortification and iodine-rich foods are available. We should ensure that we keep iodine intake on our radar and get enough iodine each day to meet our daily requirements, while still being cognizant of the other health-promoting and environmentally and animal-friendly dietary practices we may be seeking to follow.
I have included the references for this information in the text below.
References:
Poor iodine levels in women pose risks to fetal intellectual development in pregnancy https://www.sciencedaily.com/releases/2021/04/210422093858.htm
Jane S. Whitbread, Karen J. Murphy, Peter M. Clifton, Jennifer B. Keogh. Iodine Excretion and Intake in Women of Reproductive Age in South Australia Eating Plant-Based and Omnivore Diets: A Pilot Study. International Journal of Environmental Research and Public Health, 2021; 18 (7): 3547 https://www.mdpi.com/1660-4601/18/7/3547
Iodine: National Institutes of Health https://ods.od.nih.gov/factsheets/Iodine-HealthProfessional/
Iodine and Thyroid Cancer: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490680/
Iodine and Stomach and Breast Cancer and Fibrocystic Breast Disease: https://www.naturalmedicinejournal.com/journal/2014-06/iodine-and-cancer
Health Consequences of Iodine Deficiency Including Mental Developmental Problems in Children https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3074887/
Eat Smart, Live Well, Look Great!
Dr. James Meschino
Dr. James Meschino
ABOUT THE AUTHOR
Dr. James Meschino, DC, MS, ROHP, is an educator, author, and researcher having lectured to thousands of healthcare professionals across North America. He holds a Master’s Degree in Science with specialties in human nutrition and biology and is recognized as an expert in the field of nutrition, anti-aging, fitness, and wellness as well as the author of numerous books.
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